Illumina workflow solutions / Oncology Research Solutions

Transform oncology research with Illumina genomic solutions

Unlock deeper cancer biology and insights

Scientist pipetting into a tube for oncology research workflow

From sample to discovery with confidence

Illumina offers a comprehensive portfolio of oncology research workflow solutions designed to help laboratories generate high-quality, reproducible genomic insights across a broad range of cancer research applications. By integrating trusted assays, scalable sequencing platforms, and advanced data analysis, Illumina enables researchers to move efficiently from sample to discovery with confidence.

The Illumina oncology research genomic ecosystem is among the most trusted in the world. Our integrated, sample-to-data solutions reduce workflow complexity while delivering the flexibility and scalability required to support evolving research needs. This unified approach enables consistent, high-quality results that accelerate the discovery and analysis of cancer-related variants.

Portfolio breadth and flexibility

The Illumina oncology research next-generation sequencing (NGS) portfolio continues to expand to analyze a wide range of sample types, inputs, and biomarker content within a consistent workflow framework. These capabilities empower oncology researchers to study cancer biology with greater depth, consistency, and confidence.

Targeted to comprehensive

Deliver comprehensive genomic insights with choices ranging from targeted amplicon-based panels optimized for limited input samples to large hybrid-capture panels.

Tissue or liquid biopsy

Enable deeper biological insights and cross-sample analysis with support for both FFPE tissue and liquid biopsy samples offering comparable panel content.

Nucleic acid input options

Address diverse oncology research questions with flexible support for DNA, RNA, cfDNA, and cfRNA inputs.

Rapid workflows for oncology research

The NGS workflow for oncology research applications offers a rapid sample-to-report solution.

Step 1

Prepare

Scientist preparing flow cell in a lab

Innovative sample preparation

Illumina library prep kits offer future-proof content and flexibility across sample input types and throughput requirements, supporting a wide range of research and applied sequencing needs.

Automation-ready kits enable optimized liquid handling to reduce manual steps, improve consistency, and maximize lab efficiency as demand scales.

Step 2

Sequence

Scientist using sequencing system touchscreen

Recognized sequencing power

Powered by proven NGS technology and industry-leading SBS chemistry, Illumina sequencing systems provide a trusted foundation for high-performance sequencing across applications and scales.

Our comprehensive portfolio of sequencing platforms delivers scalable solutions designed to adapt as your needs evolve.

Step 3

Analyze

DRAGEN analysis chip

Reliable data sooner

DRAGEN delivers accurate, comprehensive, and efficient secondary analysis of NGS data across both local and cloud environments.

Connected tertiary analysis leverages extensive knowledge sources to streamline variant interpretation and accelerate insights with fewer touchpoints.

Oncology research genomic portfolio workflow solutions

Illumina offers genomic workflow solutions for oncology research that take you from sample to discovery.

Step 1

Prepare

Pillar oncoReveal panels

Targeted sequencing technology from Pillar Biosciences alongside Illumina sequencing and bioinformatics solutions enables rapid and focused genomic profiling of solid organ and hematologic cancers.

Step 2

Sequence

MiSeq i100

A benchtop system offering simple setup, short run times, scalable output, and exceptional data quality.

NextSeq 550

A benchtop, mid-throughput system with load-and-go reagents.

NextSeq 1000/2000

A benchtop, mid-throughput system that drives costs down and minimizes waste with XLEAP-SBS.

Step 3

Analyze

DRAGEN Secondary Analysis

DRAGEN analysis offers accurate, comprehensive, and efficient secondary analysis of NGS data available on both local and cloud-based systems.

Connected Insights Tertiary Analysis

Connected Insights analysis offers comprehensive insights and automation to support somatic oncology variant interpretation and research reporting for any assay, at any scale.

Step 1

Prepare

TruSight Oncology 500 v2

Enables CGP with a large pan-cancer panel with variants and key biomarkers from FFPE tissue.

TruSight Oncology 500 ctDNA v2

Use minimally invasive blood samples to assess circulating tumor DNA (ctDNA).

Library Prep Automation

TSO 500 library prep automation kits are formulated for use with liquid handling robots, providing optimized volumes to maximize lab efficiency.

Step 2

Sequence

NextSeq 550

A benchtop, mid-throughput system with load-and-go reagents.

NextSeq 1000/2000

A benchtop, mid-throughput system that drives costs down and minimizes waste with XLEAP-SBS.

* XLEAP-SBS chemistry is an even faster, higher quality, and more robust version of proven sequencing by synthesis chemistry.

Application and customer insights

NextSeq cartridge preparation

TruSight Oncology 500 portfolio

TSO 500 library prep automation kits are formulated for use with liquid handling robots, providing optimized volumes to maximize lab efficiency.

Connect with ERMRI

Contact our team to learn more about oncology research workflow solutions and how to apply the right genomic approach for your project.

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